KAT5 antibody (pSer90)

Catalog No. ABIN7138726

Product Details anti-KAT5 Antibody

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Binding Specificity: pSer90

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for KAT5

Target: KAT5 (K(lysine) Acetyltransferase 5 (KAT5))

Alternative Name: KAT5 (KAT5 Products)

Background:

Background:

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Kamine J., Virology 216:357-366(1996).
Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).
Legube G., Gene 310:161-168(2003).

Aliases: 60 kDa Tat interactive protein antibody, 60 kDa Tat-interactive protein antibody, cPLA(2) interacting protein antibody, cPLA(2)-interacting protein antibody, cPLA2 antibody, cPLA2 interacting protein antibody, ESA1 antibody, Histone acetyltransferase HTATIP antibody, Histone acetyltransferase KAT5 antibody, HIV 1 Tat interactive protein antibody, HIV 1 Tat interactive protein, 60 kDa antibody, HIV-1 Tat interactive protein antibody, HTATIP antibody, HTATIP1 antibody, K(lysine) acetyltransferase 5 antibody, K-acetyltransferase 5 antibody, KAT5 antibody, KAT5_HUMAN antibody, Lysine acetyltransferase 5 antibody, PLIP antibody, Tat interacting protein, 60 kDa antibody, TIP antibody, Tip60 antibody

UniProt: Q92993

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway