AKR1A1 antibody (AA 2-325)
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- Target See all AKR1A1 Antibodies
- AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))
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Binding Specificity
- AA 2-325
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This AKR1A1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Alcohol dehydrogenase [NADP(+)] protein (2-325AA)
- Isotype
- IgG
- Top Product
- Discover our top product AKR1A1 Primary Antibody
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- Application Notes
- Recommended dilution: WB:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- AKR1A1 (Aldo-Keto Reductase Family 1, Member A1 (Aldehyde Reductase) (AKR1A1))
- Alternative Name
- AKR1A1 (AKR1A1 Products)
- Background
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Background: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Aliases: AK1A1_HUMAN antibody, Akr1a1 antibody, Alcohol dehydrogenase [NADP+] antibody, Alcohol dehydrogenase antibody, Aldehyde reductase antibody, Aldo keto reductase family 1 member A1 (aldehyde reductase) antibody, Aldo-keto reductase family 1 member A1 antibody, ALDR1 antibody, ALR antibody, ARM antibody, DD3 antibody, MGC12529 antibody, MGC1380 antibody
- UniProt
- P14550
- Pathways
- Monocarboxylic Acid Catabolic Process
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