AKR1C3 antibody (AA 1-323)

Catalog No. ABIN7143694

Product Details anti-AKR1C3 Antibody

Target: AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))

Binding Specificity: AA 1-323

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKR1C3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Aldo-keto reductase family 1 member C3 protein (1-323AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AKR1C3

Target: AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))

Alternative Name: AKR1C3 (AKR1C3 Products)

Background:

Background: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.

Aliases: 17 beta HSD 5 antibody, 17 beta hydroxysteroid dehydrogenase type 5 antibody, 17-beta-HSD 5 antibody, 17-beta-hydroxysteroid dehydrogenase type 5 antibody, 2-dihydrobenzene-1 antibody, 2-diol dehydrogenase antibody, 20 alpha-hydroxysteroid dehydrogenase antibody, 20-alpha-hydroxysteroid dehydrogenase antibody, 3 alpha hydroxysteroid dehydrogenase type II antibody, 3-alpha-HSD type 2 antibody, 3-alpha-HSD type II antibody, 3-alpha-HSD type II, brain antibody, 3-alpha-hydroxysteroid dehydrogenase type 2 antibody, AK1C3_HUMAN antibody, AKR1 C3 antibody, Akr1c18 antibody, AKR1C3 antibody, Aldo keto reductase family 1 member C3 antibody, Aldo-keto reductase family 1 member C3 antibody, brain antibody, Chlordecone reductase antibody, Chlordecone reductase homolog HAKRb antibody, DD-3 antibody, DD3 antibody, DDH1 antibody, DDX antibody, Dihydrodiol dehydrogenase 3 antibody, Dihydrodiol dehydrogenase type I antibody, Dihydrodiol dehydrogenase X antibody, HA1753 antibody, HAKRB antibody, HAKRe antibody, hluPGFS antibody, HSD17B5 antibody, Indanol dehydrogenase antibody, KIAA0119 antibody, PGFS antibody, Prostaglandin F synthase antibody, Testosterone 17-beta-dehydrogenase 5 antibody, Trans-1 antibody, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase antibody, Type IIb 3 alpha hydroxysteroid dehydrogenase antibody

UniProt: P42330

Pathways: Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus