APOBEC3A antibody (AA 1-199)

Catalog No. ABIN7150146

Product Details anti-APOBEC3A Antibody

Target: APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))

Binding Specificity: AA 1-199

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC3A antibody is un-conjugated

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA dC->dU-editing enzyme APOBEC-3A protein (1-199AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for APOBEC3A

Target: APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))

Alternative Name: APOBEC3A (APOBEC3A Products)

Background:

Background: DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

Aliases: A3A antibody, ABC3A_HUMAN antibody, APOBEC3A antibody, Apolipoprotein B mRNA editing enzyme antibody, Apolipoprotein B mRNA editing enzyme, catalytic polypeptide like 3A antibody, ARP3 antibody, bK150C2.1 antibody, Catalytic polypeptide like 3A antibody, Phorbolin 1 antibody, Phorbolin-1 antibody, PHRBN antibody, Probable DNA dC >dU editing enzyme APOBEC-3A antibody, Probable DNA dC->dU-editing enzyme APOBEC-3A antibody

UniProt: P31941