IGF2BP3 antibody (AA 1-100)

Catalog No. ABIN7156360

Product Details anti-IGF2BP3 Antibody

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2BP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Insulin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IGF2BP3

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Alternative Name: IGF2BP3 (IGF2BP3 Products)

Background:

Background: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript \\\'caging\\\' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3\\\'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5\\\'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Aliases: Cancer/testis antigen 98 antibody, CT98 antibody, DKFZp686F1078 antibody, hKOC antibody, IF2B3_HUMAN antibody, IGF II mRNA binding protein 3 antibody, IGF-II mRNA-binding protein 3 antibody, IGF2 mRNA binding protein 3 antibody, IGF2 mRNA-binding protein 3 antibody, IGF2BP3 antibody, IMP 3 antibody, IMP-3 antibody, Insulin like growth factor 2 mRNA binding protein 3 antibody, Insulin-like growth factor 2 mRNA-binding protein 3 antibody, KH domain containing protein overexpressed in cancer antibody, KH domain-containing protein overexpressed in cancer antibody, KOC 1 antibody, KOC1 antibody, VICKZ 3 antibody, VICKZ family member 3 antibody, VICKZ3 antibody

UniProt: O00425