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NR2C1 antibody (AA 1-240)

NR2C1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7161902
  • Target See all NR2C1 Antibodies
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Binding Specificity
    • 9
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-240
    Reactivity
    • 54
    • 17
    • 11
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 48
    • 8
    Rabbit
    Clonality
    • 52
    • 4
    Polyclonal
    Conjugate
    • 39
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR2C1 antibody is un-conjugated
    Application
    • 48
    • 19
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Nuclear receptor subfamily 2 group C member 1 protein (1-240AA)
    Isotype
    IgG
    Top Product
    Discover our top product NR2C1 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))
    Alternative Name
    NR2C1 (NR2C1 Products)
    Background

    Background: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5\\\'-AGGTCA-3\\\' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

    Aliases: NR2C1 antibody, TR2 antibody, Nuclear receptor subfamily 2 group C member 1 antibody, Orphan nuclear receptor TR2 antibody, Testicular receptor 2 antibody

    UniProt
    P13056
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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