FKBP4 antibody (AA 220-459)

Catalog No. ABIN7162842

Product Details anti-FKBP4 Antibody

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Binding Specificity: AA 220-459

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP4 protein (220-459AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FKBP4

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Alternative Name: FKBP4 (FKBP4 Products)

Background:

Background: Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

Aliases: 51 kDa FK506-binding protein antibody, 52 kDa FK506 binding protein antibody, 52 kDa FK506-binding protein antibody, 52 kDa FKBP antibody, 59 kDa immunophilin antibody, FK506 binding protein 4 antibody, FK506-binding protein 4 antibody, FKBP 4 antibody, FKBP 52 antibody, FKBP 59 antibody, FKBP-4 antibody, FKBP-52 antibody, FKBP4 antibody, FKBP4_HUMAN antibody, FKBP51 antibody, FKBP52 protein antibody, FKBP59 antibody, HBI antibody, Hsp 56 antibody, HSP binding immunophilin antibody, HSP-binding immunophilin antibody, Hsp56 antibody, Immunophilin FKBP52 antibody, N-terminally processed antibody, p52 antibody, p59 antibody, p59 protein antibody, Peptidyl prolyl cis trans isomerase antibody, peptidyl-prolyl cis-trans isomerase antibody, Peptidyl-prolyl cis-trans isomerase FKBP4 antibody, Peptidylprolyl cis trans isomerase antibody, PPIase antibody, PPIase FKBP4 antibody, Rotamase antibody, T cell FK506 binding protein 59kD antibody

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway