PPM1A antibody (AA 1-382)

Catalog No. ABIN7165941

Product Details anti-PPM1A Antibody

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Binding Specificity: AA 1-382

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Protein phosphatase 1A protein (1-382AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Alternative Name: PPM1A (PPM1A Products)

Synonyms: PP2C-ALPHA antibody, PP2CA antibody, PP2Calpha antibody, 2310003C21Rik antibody, 2900017D14Rik antibody, AI427932 antibody, AU017636 antibody, MMPa-2 antibody, MPPa-1 antibody, Pp2c1 antibody, pp2c-alpha antibody, pp2ca antibody, pp2calpha antibody, pp2ca2 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1A antibody, protein phosphatase 1A, magnesium dependent, alpha isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1A antibody, protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Aa antibody, PPM1A antibody, Ppm1a antibody, ppm1a.L antibody, ppm1aa antibody

Background:

Background: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.

Aliases: Protein phosphatase 2C isoform alpha antibody, EC 3.1.3.16 antibody, FLJ42306 antibody, IA antibody, MGC9201 antibody, Mpp alpha antibody, PP2C alpha antibody, PP2C-alpha antibody, PP2CA antibody, PP2Calpha antibody, PPM 1A antibody, PPM1A antibody, PPM1A_HUMAN antibody, PPPM1A antibody, Protein phosphatase 1A (formerly 2C) magnesium dependent alpha isoform antibody, Protein phosphatase 1A antibody, Protein phosphatase 1A magnesium dependent alpha antibody, Protein phosphatase 2C alpha antibody, Protein phosphatase 2C alpha isoform antibody, Protein phosphatase 2C isoform alpha antibody, Protein phosphatase IA antibody, Protein phosphatase, Mg2+/Mn2+ dependent, 1A antibody

UniProt: P35813