SEMA5A antibody (AA 201-400)
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- Target See all SEMA5A Antibodies
- SEMA5A (Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A))
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Binding Specificity
- AA 201-400
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SEMA5A antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Semaphorin-5A protein (201-400AA)
- Isotype
- IgG
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anti-Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A) (N-Term) antibody
SEMA5A Reactivity: Mouse WB Host: Rabbit Polyclonal RB9479 unconjugated
anti-Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A) (AA 90-113) antibodySEMA5A Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB16634 unconjugated
anti-Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A) (AA 1006-1035) antibodySEMA5A Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB8966 unconjugated
anti-Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A) (AA 393-499) antibodySEMA5A Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A) (AA 700-1000) antibodySEMA5A Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SEMA5A (Sema Domain, Seven thrombospondin Repeats (Type 1 and Type 1-Like), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 5A (SEMA5A))
- Alternative Name
- SEMA5A (SEMA5A Products)
- Background
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Background: Bifunctional axonal guidance cue regulated by sulfated proteoglycans, attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
Aliases: SEMA5A antibody, SEMAF antibody, Semaphorin-5A antibody, Semaphorin-F antibody, Sema F antibody
- UniProt
- Q13591
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