ZMYND11 antibody (AA 363-513)

Catalog No. ABIN7176097

Product Details anti-ZMYND11 Antibody

Target: ZMYND11 (Zinc Finger, MYND-Type Containing 11 (ZMYND11))

Binding Specificity: AA 363-513

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZMYND11 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Zinc finger MYND domain-containing protein 11 protein (363-513AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ZMYND11

Target: ZMYND11 (Zinc Finger, MYND-Type Containing 11 (ZMYND11))

Alternative Name: ZMYND11 (ZMYND11 Products)

Background:

Background: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at \\\'Lys-36\\\' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Aliases: ZMYND11 antibody, BRAM1 antibody, BS69 antibody, Zinc finger MYND domain-containing protein 11 antibody, Adenovirus 5 E1A-binding protein antibody, Bone morphogenetic protein receptor-associated molecule 1 antibody, Protein BS69 antibody

UniProt: Q15326