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CD79a antibody

CD79A Reactivity: Human IHC, ELISA Host: Mouse Monoclonal unconjugated
Catalog No. ABIN7180757
  • Target See all CD79a (CD79A) Antibodies
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    Reactivity
    • 181
    • 93
    • 74
    • 53
    • 52
    • 34
    • 29
    • 27
    • 27
    • 27
    • 17
    • 10
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 95
    • 94
    • 1
    Mouse
    Clonality
    • 117
    • 72
    • 1
    Monoclonal
    Conjugate
    • 93
    • 17
    • 13
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD79a antibody is un-conjugated
    Application
    • 118
    • 80
    • 62
    • 48
    • 44
    • 24
    • 22
    • 14
    • 10
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human
    Purification
    Affinity purified
    Immunogen
    Synthesized peptide derived from human CD79a
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD79A Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    Alternative Name
    CD79A (CD79A Products)
    Background

    Background: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

    Aliases: B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a), CD79A, IGA MB1

    UniProt
    P11912
    Pathways
    BCR Signaling
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