CD79a antibody
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- Target See all CD79a (CD79A) Antibodies
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD79a antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human
- Purification
- Affinity purified
- Immunogen
- Synthesized peptide derived from human CD79a
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product CD79A Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
- Alternative Name
- CD79A (CD79A Products)
- Background
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Background: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Aliases: B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a), CD79A, IGA MB1
- UniProt
- P11912
- Pathways
- BCR Signaling
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