EIF2S2 antibody (N-Term)

Catalog No. ABIN7184449

Product Details anti-EIF2S2 Antibody

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2S2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from N-terminal of Human eIF2B.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:3000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EIF2S2

Target: EIF2S2 (Eukaryotic Translation Initiation Factor 2, Subunit 2 Beta, 38kDa (EIF2S2))

Alternative Name: EIF2S2 (EIF2S2 Products)

Background:

Background: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Pathak V.K., Cell 54:633-639(1988).
Deloukas P., Nature 414:865-871(2001).
Olsen J.V., Cell 127:635-648(2006).

Aliases: DKFZp686L18198 antibody, eIF 2 beta antibody, eIF-2-beta antibody, EIF2 antibody, EIF2B antibody, EIF2beta antibody, EIF2S2 antibody, Eukaryotic initiation factor 2 beta antibody, eukaryotic initiation factor 2-beta antibody, Eukaryotic translation initiation factor 2 beta antibody, Eukaryotic translation initiation factor 2 subunit 2 antibody, Eukaryotic translation initiation factor 2 subunit 2 beta 38 kDa antibody, Eukaryotic translation initiation factor 2 subunit 2 beta antibody, Eukaryotic translation initiation factor 2 subunit beta antibody, eukaryotic translation initiation factor 2, subunit 2 beta, 38 kDa antibody, IF2B_HUMAN antibody, MGC8508 antibody, PPP1R67 antibody, protein phosphatase 1, regulatory subunit 67 antibody

UniProt: P20042