GZMK antibody (AA 27-264)

Catalog No. ABIN7193832

Product Details anti-GZMK Antibody

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Binding Specificity: AA 27-264

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GZMK antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Purpose: GZMK Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human GZMK (AA: 27-264) expressed in E. Coli.

Clone: 2F9C12

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Alternative Name: GZMK (GZMK Products)

Background:

Description:

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]

Aliases: TRYP2

Molecular Weight: 29kda

Gene ID: 3003

UniProt: P49863