IVD antibody (AA 33-200)

Catalog No. ABIN7268031

Product Details anti-IVD Antibody

Target: IVD (Isovaleryl-CoA Dehydrogenase (IVD))

Binding Specificity: AA 33-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IVD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: IVD Rabbit pAb

Sequence: HSLLPVDDAI NGLSEEQRQL RQTMAKFLQE HLAPKAQEID RSNEFKNLRE FWKQLGNLGV LGITAPVQYG GSGLGYLEHV LVMEEISRAS GAVGLSYGAH SNLCINQLVR NGNEAQKEKY LPKLISGEYI GALAMSEPNA GSDVVSMKLK AEKKGNHYIL NGNKFWIT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 33-200 of human IVD (NP_002216.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IVD

Target: IVD (Isovaleryl-CoA Dehydrogenase (IVD))

Alternative Name: IVD (IVD Products)

Background: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,IVD,ACAD2,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,IVD

Molecular Weight: 42kDa/46kDa

Gene ID: 3712

UniProt: P26440

Pathways: Monocarboxylic Acid Catabolic Process