LOXL2 antibody (AA 505-774)

Catalog No. ABIN7268349

Product Details anti-LOXL2 Antibody

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Binding Specificity: AA 505-774

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: LOXL2 Rabbit pAb

Sequence: VMSGVKCSGT ELSLAHCRHD GEDVACPQGG VQYGAGVACS ETAPDLVLNA EMVQQTTYLE DRPMFMLQCA MEENCLSASA AQTDPTTGYR RLLRFSSQIH NNGQSDFRPK NGRHAWIWHD CHRHYHSMEV FTHYDLLNLN GTKVAEGHKA SFCLEDTECE GDIQKNYECA NFGDQGITMG CWDMYRHDID CQWVDITDVP PGDYLFQVVI NPNFEVAESD YSNNIMKCRS RYDGHRIWMY NCHIGGSFSE ETEKKFEHFS GLLNNQLSPQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 505-774 of human LOXL2 (NP_002309.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LOXL2

Target: LOXL2 (Lysyl Oxidase-Like 2 (LOXL2))

Alternative Name: LOXL2 (LOXL2 Products)

Background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.,LOXL2,LOR,LOR2,WS9-14,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,LOXL2

Molecular Weight: 86kDa

Gene ID: 4017

UniProt: Q9Y4K0

Pathways: Chromatin Binding