PLEKHG4 antibody (AA 710-1010)

Catalog No. ABIN7269416

Product Details anti-PLEKHG4 Antibody

Target: PLEKHG4 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4))

Binding Specificity: AA 710-1010

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHG4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PLEKHG4 Rabbit pAb

Sequence: GALPQASPTV PPPGSSDPRS LNRLQLVLAE MVATEREYVR ALEYTMENYF PELDRPDVPQ GLRGQRAHLF GNLEKLRDFH CHFFLRELEA CTRHPPRVAY AFLRHRVQFG MYALYSKNKP RSDALMSSYG HTFFKDKQQA LGDHLDLASY LLKPIQRMGK YALLLQELAR ACGGPTQELS ALREAQSLVH FQLRHGNDLL AMDAIQGCDV NLKEQGQLVR QDEFVVRTGR HKSVRRIFLF EELLLFSKPR HGPTGVDTFA YKRSFKMADL GLTECCGNSN LRFEIWFRRR KARDTFVLQA S

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 710-1010 of human PLEKHG4 (NP_001123199.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLEKHG4

Target: PLEKHG4 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 4 (PLEKHG4))

Alternative Name: PLEKHG4 (PLEKHG4 Products)

Background: The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants.,PLEKHG4,ARHGEF44,PRTPHN1,SCA4,Neuroscience,Neurodegenerative Diseases,PLEKHG4

Molecular Weight: 20kDa/122kDa/130kDa

Gene ID: 25894

UniProt: Q58EX7