Kv3.4 antibody (AA 490-538)

Catalog No. ABIN7269488

Product Details anti-Kv3.4 Antibody

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Binding Specificity: AA 490-538

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv3.4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: KCNC4 Rabbit pAb

Sequence: KKRKKHVPRP AQLESPMYCK SEETSPRDST CSDTSPPARE EGMIERKRA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 490-538 of human KCNC4 (NP_004969.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Kv3.4

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Alternative Name: KCNC4 (KCNC4 Products)

Background: The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.,KCNC4,C1orf30,HKSHIIIC,KSHIIIC,KV3.4,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,KCNC4

Molecular Weight: 64kDa/68kDa/69kDa

Gene ID: 3749

UniProt: Q03721