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- Target See all TOPORS Antibodies
- TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TOPORS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Topors Rabbit pAb
- Cross-Reactivity
- Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human Topors.
- Isotype
- IgG
- Top Product
- Discover our top product TOPORS Primary Antibody
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anti-Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS) (AA 98-205) antibody
TOPORS Reactivity: Human WB, ELISA, IHC (p), IF Host: Mouse Monoclonal 5G11 unconjugated
anti-Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS) (AA 98-206) antibodyTOPORS Reactivity: Human WB, ELISA, IHC, IHC (p), IF Host: Mouse Monoclonal 5G11 unconjugated
anti-Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS) (C-Term) antibodyTOPORS Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS) (AA 98-205) antibodyTOPORS Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TOPORS (Topoisomerase I Binding, arginine/serine-Rich, E3 Ubiquitin Protein Ligase (TOPORS))
- Alternative Name
- Topors (TOPORS Products)
- Background
- Functions as an E3 ubiquitin-protein ligase and as a E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA-damage-induced cell death through IKBKE sumoylation.,AW105885,LUN,TP53BPL,p53BP3/LUN,Topors,Topors
- Gene ID
- 106021
- UniProt
- Q80Z37
- Pathways
- Maintenance of Protein Location
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