ZNF384 antibody (AA 1-180)

Catalog No. ABIN7271478

This anti-ZNF384 antibody is a Rabbit Polyclonal antibody detecting ZNF384 in WB and IHC. Suitable for Human.

Quick Overview for ZNF384 antibody (AA 1-180) (ABIN7271478)

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF384 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ZNF384 Antibody

Binding Specificity: AA 1-180

Purpose: ZNF384 Rabbit pAb

Sequence: MEESHFNSNP YFWPSIPTVS GQIENTMFIN KMKDQLLPEK GCGLAPPHYP TLLTVPASVS LPSGISMDTE SKSDQLTPHS QASVTQNITV VPVPSTGLMT AALQVVPDLS KKVASTLTEE GGGGGGGGGS VAPKPPRGRK KKRMLESGLP EMNDPYVLSP EDDDDHQKDG KTYRCRMCSL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ZNF384 (NP_001035009.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZNF384

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Alternative Name: ZNF384

Background: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.,ZNF384,CAGH1,CAGH1A,CIZ,ERDA2,NMP4,NP,TNRC1,Epigenetics & Nuclear Signaling,Transcription Factors,ZNF384

Molecular Weight: 50kDa/56kDa/63kDa

Gene ID: 171017

UniProt: Q8TF68