ZNF384 antibody (AA 1-180)
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- Target See all ZNF384 Antibodies
- ZNF384 (Zinc Finger Protein 384 (ZNF384))
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Binding Specificity
- AA 1-180
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ZNF384 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purpose
- ZNF384 Rabbit pAb
- Sequence
- MEESHFNSNP YFWPSIPTVS GQIENTMFIN KMKDQLLPEK GCGLAPPHYP TLLTVPASVS LPSGISMDTE SKSDQLTPHS QASVTQNITV VPVPSTGLMT AALQVVPDLS KKVASTLTEE GGGGGGGGGS VAPKPPRGRK KKRMLESGLP EMNDPYVLSP EDDDDHQKDG KTYRCRMCSL
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ZNF384 (NP_001035009.1).
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ZNF384 (Zinc Finger Protein 384 (ZNF384))
- Alternative Name
- ZNF384 (ZNF384 Products)
- Background
- This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.,ZNF384,CAGH1,CAGH1A,CIZ,ERDA2,NMP4,NP,TNRC1,Epigenetics & Nuclear Signaling,Transcription Factors,ZNF384
- Molecular Weight
- 50kDa/56kDa/63kDa
- Gene ID
- 171017
- UniProt
- Q8TF68
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