Envoplakin antibody (AA 1275-1325)

Catalog No. ABIN7449223

Product Details anti-Envoplakin Antibody

Target: Envoplakin (EVPL)

Binding Specificity: AA 1275-1325

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Envoplakin antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-EVPL Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1275 and 1325

Isotype: IgG

Application Details

Application Notes: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Envoplakin

Target: Envoplakin (EVPL)

Alternative Name: EVPL (EVPL Products)

Background: Background: Envoplakin is a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. The gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated with both familial and sporadic forms of oesophageal squamous cell carcinoma. Patients suffering from the autoimmune mucocutaneous disorder, paraneoplastic pemphigus, develop antibodies against Envoplakin [taken from NCBI Entrez Gene (Gene ID: 2125)].

Gene ID: 2125

UniProt: Q92817