LRPPRC antibody (AA 1344-1394)

Catalog No. ABIN7455051

Product Details anti-LRPPRC Antibody

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Binding Specificity: AA 1344-1394

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRPPRC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-LRPPRC Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1344 and 1394

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for LRPPRC

Target: LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))

Alternative Name: LRPPRC (LRPPRC Products)

Background: Background: LRPPRC is a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome [taken from NCBI Entrez Gene (Gene ID: 10128)].

Gene ID: 10128

NCBI Accession: NP_573566

UniProt: P42704