The mouse monoclonal antibody 5D12 recognizes an extracellular epitope of human NKp80 (CLEC5C), a C-type lectin family member, expressed on NK cells and subsets of T cells.
CLEC5C antibody, NKp80 antibody, KLRF1 antibody, Lectin-like receptor F1 antibody, nkp80 antibody, killer cell lectin like receptor F1 antibody, KLRF1 antibody
Background
Killer cell lectin like receptor F1,NKp80, also known as CLEC5C or KLRF1, is a type II transmembrane glycoprotein of the C lectin family, which is expressed in 80 kDa homodimers on NK cells, and subsets of CD8+ alpha/beta T cells, and gamma/delta T cells. It belongs to the activating coreceptors, which induce cytotoxicity, and production of pro-inflammatory cytokines. Its ligand AICL is expressed on myeloid cells.,KLRF1, CLEC5C