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IDH3A antibody (AA 281-366) (HRP)

IDH3A Reactivity: Human, Rat WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN751552
  • Target See all IDH3A Antibodies
    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
    Binding Specificity
    • 14
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 281-366
    Reactivity
    • 43
    • 30
    • 17
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 39
    • 3
    • 1
    Rabbit
    Clonality
    • 41
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IDH3A antibody is conjugated to HRP
    Application
    • 32
    • 13
    • 13
    • 10
    • 10
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IDH3A
    Isotype
    IgG
    Top Product
    Discover our top product IDH3A Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
    Alternative Name
    Idh3a (IDH3A Products)
    Synonyms
    idh3a antibody, MGC76128 antibody, IDH3A antibody, zgc:56380 antibody, zgc:85631 antibody, BG1 antibody, 1110003P10Rik antibody, 1500012E04Rik antibody, AA407078 antibody, AI316514 antibody, isocitrate dehydrogenase 3 (NAD+) alpha antibody, isocitrate dehydrogenase 3 (NAD(+)) alpha antibody, isocitrate dehydrogenase 3 (NAD+) alpha S homeolog antibody, idh3a antibody, IDH3A antibody, idh3a.S antibody, Idh3a antibody
    Background

    Synonyms: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha, IDH3A

    Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Gene ID
    3419
    UniProt
    P50213
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