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Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A) (AA 310-360) antibody (HRP) Primary Antibody

IDH3A Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal HRP
Catalog No. ABIN751552
$442.20
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A)
    Binding Specificity
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 310-360
    Reactivity
    • 35
    • 27
    • 26
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 30
    • 4
    • 1
    Rabbit
    Clonality
    • 32
    • 3
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    HRP
    Application
    • 19
    • 13
    • 9
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IDH3A
    Isotype
    IgG
  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
    Preservative
    Gentamicin sulfate
    Precaution of Use
    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    4 °C
    Storage Comment
    Store at 4°C
    Expiry Date
    12 months
  • Target
    Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A)
    Alternative Name
    Idh3a (IDH3A Antibody Abstract)
    Synonyms
    idh3a, MGC76128, IDH3A, zgc:56380, zgc:85631, BG1, 1110003P10Rik, 1500012E04Rik, AA407078, AI316514, isocitrate dehydrogenase 3 (NAD+) alpha, isocitrate dehydrogenase 3 (NAD(+)) alpha, isocitrate dehydrogenase 3 (NAD+) alpha S homeolog, idh3a, IDH3A, idh3a.S, Idh3a
    Background

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. IDH3A is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Subcellular location: Mitochondrion

    Synonyms: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitric dehydrogenase subunit alpha, NAD(+)-specific ICDH subunit alpha, IDH3A

    Gene ID
    3419
    UniProt
    P50213
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