IDH3A antibody (AA 28-366)

Catalog No. ABIN7268029

This Rabbit Polyclonal antibody specifically detects IDH3A in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for IDH3A antibody (AA 28-366) (ABIN7268029)

Target: IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDH3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IDH3A Antibody

Binding Specificity: AA 28-366

Purpose: IDH3A Rabbit pAb

Sequence: TGGVQTVTLI PGDGIGPEIS AAVMKIFDAA KAPIQWEERN VTAIQGPGGK WMIPSEAKES MDKNKMGLKG PLKTPIAAGH PSMNLLLRKT FDLYANVRPC VSIEGYKTPY TDVNIVTIRE NTEGEYSGIE HVIVDGVVQS IKLITEGASK RIAEFAFEYA RNNHRSNVTA VHKANIMRMS DGLFLQKCRE VAESCKDIKF NEMYLDTVCL NMVQDPSQFD VLVMPNLYGD ILSDLCAGLI GGLGVTPSGN IGANGVAIFE SVHGTAPDIA GKDMANPTAL LLSAVMMLRH MGLFDHAARI EAACFATIKD GKSLTKDLGG NAKCSDFTEE ICRRVKDLD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-366 of human IDH3A (NP_005521.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IDH3A

Target: IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Alternative Name: IDH3A

Background: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.,IDH3A,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,IDH3A

Molecular Weight: 31kDa/40kDa

Gene ID: 3419

UniProt: P50213