RASA2 antibody (RAS P21 Protein Activator 2) (Cy3) Primary Antibody
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- Target
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Polyclonal
- Conjugate
- This RASA2 antibody is conjugated to Cy3
- Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human RASGAP
- Isotype
- IgG
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C
- Expiry Date
- 12 months
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- Target
- Alternative Name
- Rasa2 (RASA2 Antibody Abstract)
- Background
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein, a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008].
Synonyms: GAP1M, GTPase activating protein of RAS, Ras GTPase activating protein 2, Ras GTPase-activating protein 2, RAS p21 protein activator 2, RASA2, RASA2_HUMAN, RASGAP.
- Gene ID
- 8826
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