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RASA2 antibody (RAS P21 Protein Activator 2) (AA 765-849) (Biotin) Primary Antibody

RASA2 Reactivity: Human ELISA, IHC (fro), IHC (p), WB Host: Rabbit Polyclonal Biotin
Catalog No. ABIN763468
$419.10
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    RASA2
    Binding Specificity
    • 13
    • 1
    AA 765-849
    Reactivity
    • 19
    • 2
    • 2
    Human
    Host
    • 19
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RASA2 antibody is conjugated to Biotin
    Application
    • 13
    • 12
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Cross-Reactivity
    Cow, Dog, Horse, Human, Mouse, Rabbit, Rat, Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RASGAP
    Isotype
    IgG
  • Application Notes
    WB 1:300-1000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Target
    RASA2
    Alternative Name
    RASA2 (RASA2 Antibody Abstract)
    Synonyms
    GAP1M, 5430433H21Rik, AA517451, AU023900, GAP1m, RAS p21 protein activator 2, RASA2, Rasa2
    Background

    The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member has a perinuclear localization and is an inositol 1,3,4,5-tetrakisphosphate-binding protein, a compound suggested to function as a second messenger. [provided by RefSeq, Jul 2008].

    Subcellular location: Cytoplasm

    Synonyms: GAP1M, GTPase activating protein of RAS, Ras GTPase activating protein 2, Ras GTPase-activating protein 2, RAS p21 protein activator 2, RASA2, RASA2_HUMAN, RASGAP.

    Gene ID
    8826
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