CRISP2 antibody (N-Term)

Catalog No. ABIN783679

This Rabbit Polyclonal antibody specifically detects CRISP2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for CRISP2 antibody (N-Term) (ABIN783679)

Target: CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRISP2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CRISP2 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects CRISP2 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human CRISP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for CRISP2

Target: CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

Alternative Name: CRISP2

Background: The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.Synonyms: CRISP-2, CT36, Cancer/testis antigen 36, Cysteine-rich secretory protein 2, GAPDL5, TPX1, Testis-specific protein TPX-1

Gene ID: 7180

NCBI Accession: NP_001135879

UniProt: P16562