PIWIL1 antibody (N-Term)
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- Target See all PIWIL1 Antibodies
- PIWIL1 (Piwi-Like 1 (PIWIL1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PIWIL1 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody detects PIWIL1 at N-term.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 18 amino acid peptide near the amino terminus of human PIWI-L1
- Top Product
- Discover our top product PIWIL1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- Target
- PIWIL1 (Piwi-Like 1 (PIWIL1))
- Alternative Name
- PIWIL1 (PIWIL1 Products)
- Background
- PIWI-L1 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L1 is thought to play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells as removing PIWI-L1 protein from single germline stem cells significantly decreases the rate of their division. Recent studies have shown that overexpression of PIWI-L1 (as well as other PIWI-like proteins) are potential biomarkers for colon and other cancers.Synonyms: HIWI, Piwi-like protein 1
- Gene ID
- 9271
- NCBI Accession
- NP_001177900
- UniProt
- Q96J94
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