SLC1A5 antibody (Internal Region)

Catalog No. ABIN784185

This anti-SLC1A5 antibody is a Rabbit Polyclonal antibody detecting SLC1A5 in IHC (p). Suitable for Human.

Quick Overview for SLC1A5 antibody (Internal Region) (ABIN784185)

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC1A5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SLC1A5 Antibody

Binding Specificity: Internal Region

Specificity: Human SLC1A5

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to internal domain of Human SLC1A5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLC1A5

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Alternative Name: SLC1A5

Background: Solute Carrier Family 1 Member 5 (Slc1a5/ASCT2) belongs to a family of sodium dependent amino acid transporters. Slc1a5 has a preference for transporting zwitter ions. Slc1a5 also functions as a cell surface receptor for endogenously inherited retroviruses of cats, baboons and humans as well as for horizontally transmitted type-D simian retroviruses. In addition, it has been associated with increased metabolism in malignant tumors. In prostate carcinoma ASCT2 positivity is correlated with more aggressive biological behavior.Synonyms: ASCT2, ATB(0), Baboon M7 virus receptor, M7V1, Neutral amino acid transporter B(0), RD114/simian type D retrovirus receptor, RDR, RDRC, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5

Gene ID: 6510

NCBI Accession: NP_005619

Pathways: Dicarboxylic Acid Transport, Warburg Effect