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Pseudouridylate Synthase 10 (PUS10) antibody Primary Antibody

PUS10 Reactivity: Human, Mouse, Rat IF (p), IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN873013
$339.90
Plus shipping costs $45.00
100 μL
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Delivery in 4 to 6 Business Days
  • Target
    Pseudouridylate Synthase 10 (PUS10)
    Reactivity
    Human, Mouse, Rat
    • 37
    • 20
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Host
    Rabbit
    • 37
    Clonality
    Polyclonal
    Conjugate
    Un-conjugated
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 25
    • 17
    • 12
    • 3
    • 2
    • 1
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PUS10/CCDC139
    Isotype
    IgG
  • Application Notes
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    Pseudouridylate Synthase 10 (PUS10)
    Alternative Name
    Ccdc139 (PUS10 Antibody Abstract)
    Synonyms
    CCDC139, DOBI, 2810013G11Rik, 4933435A13Rik, AU014648, C77560, Ccdc139, RGD1306402, pseudouridylate synthase 10, PUS10, Pus10
    Background

    Pseudouridination is the isomerization of uridine to pseudouridine. It is the most common posttranscriptional nucleotide modification found in RNA. It is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones which facilitate the correct folding and assembly of tRNAs.

    Synonyms: CCDC139, Coiled coil domain containing protein 139, DOBI, FLJ32312, MGC126729, Putative tRNA pseudouridine synthase Pus10, tRNA pseudouridine 55 synthase, tRNA uridine isomerase, PUS10_HUMAN.

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