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Lamin B Receptor antibody (LBR) (AA 1-100) (Alexa Fluor 647) Primary Antibody

LBR Reactivity: Human, Mouse FACS Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN904408
$442.20
Plus shipping costs $45.00
100 μL
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  • Target
    Lamin B Receptor (LBR)
    Binding Specificity
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 28
    • 20
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 26
    • 2
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lamin B Receptor antibody is conjugated to Alexa Fluor 647
    Application
    • 15
    • 14
    • 6
    • 6
    • 4
    • 4
    • 1
    Flow Cytometry (FACS)
    Specificity
    The immunogen for this product has partial sequence similarity to SEPT8 and SEPT2
    Cross-Reactivity
    Cow, Horse, Rabbit, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Lamin B Receptor
    Isotype
    IgG
  • Application Notes
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4 °C
    Expiry Date
    12 months
  • Target
    Lamin B Receptor (LBR)
    Alternative Name
    Lamin B Receptor (LBR Antibody Abstract)
    Synonyms
    CG17952, Dmel\\CG17952, dLBR, sb:cb406, zgc:86649, wu:fb75h08, wu:fc47b04, wu:fd36b07, lbr-A, Xp58, p58 gene, LBR, DHCR14B, LMN2R, PHA, TDRD18, AI505894, ic, Nbp60, lamin B receptor, Lamin B receptor, lamin B receptor S homeolog, LBR, lbr, lbr.S, Lbr
    Background

    Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

    Subcellular location: Cytoplasm, Nucleus, Cell membrane

    Synonyms: PHA, LMN2R, TDRD18, DHCR14B, Lamin-B receptor, Integral nuclear envelope inner membrane protein, LBR

    Gene ID
    3930
    UniProt
    Q14739
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