VLDLR antibody (PE-Cy5.5)

Catalog No. ABIN919767

Product Details anti-VLDLR Antibody (PE-Cy5.5)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reactivity: Human, Rat, Mouse, Dog, Pig, Chicken, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VLDLR antibody is conjugated to PE-Cy5.5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VLDL Receptor

Isotype: IgG

Application Details

Application Notes: WB(1:100-500)
FCM(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-VLDLR antibody (PE-Cy5.5) (ABIN919767)

Fredriksson, Mishra, Lam, Mushaben, Cuento, Meyer, Yao, Keeran, Nugent, Qu, Yu, Yang, Raghavachari, Dagur, McCoy, Levine: "The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 10, pp. 4497-509, (2014) (PubMed).

Target Details for VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Alternative Name: VLDL Receptor (VLDLR Products)

Background:

Synonyms: CARMQ1, CHRMQ1, VLDLRCH, Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Background: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).

Molecular Weight: 95-130kDa

Gene ID: 7436

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin