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Cytokeratin 18 antibody (Keratin 18) Primary Antibody

KRT18 Reactivity: Human ICC, FACS, IHC (p), IP, ELISA, WB Host: Mouse Monoclonal DC-10 unconjugated
Pubmed (4)
Catalog No. ABIN94282
$364.32
Plus shipping costs $45.00
0.1 mg
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  • Target
    Cytokeratin 18 (KRT18)
    Reactivity
    • 327
    • 157
    • 125
    • 63
    • 43
    • 43
    • 38
    • 33
    • 30
    • 26
    • 24
    • 22
    • 22
    • 22
    • 9
    • 9
    • 8
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 185
    • 158
    • 7
    • 7
    • 3
    • 2
    • 1
    Mouse
    Clonality
    • 202
    • 161
    Monoclonal
    Conjugate
    • 169
    • 29
    • 23
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    This Cytokeratin 18 antibody is un-conjugated
    Application
    • 227
    • 135
    • 130
    • 110
    • 85
    • 68
    • 58
    • 54
    • 41
    • 40
    • 33
    • 27
    • 12
    • 10
    • 8
    • 7
    • 2
    • 1
    Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
    Specificity
    The antibody DC-10 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
    No Cross-Reactivity
    Pig (Porcine), Mouse (Murine), Rat (Rattus), Hamster, Cow (Bovine), Dog (Canine), Sheep (Ovine)
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    Human breast carcinoma cell line PMC-42.
    Clone
    DC-10
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
  • Ta: "Primary human hepatocytes on biodegradable poly(l-lactic acid) matrices: a promising model for improving transplantation efficiency with tissue engineering." in: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, Vol. 17, Issue 2, pp. 104-14, 2011 (PubMed).

    Vojt?sek, Stasková, Nenutil, Lauerová, Kovarík, Rejthar, Bártková, Bártek: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." in: Folia biologica, Vol. 35, Issue 6, pp. 373-82, 1990 (PubMed).

    Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." in: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, 1989 (PubMed).

    Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989 (PubMed).

  • Target
    Cytokeratin 18 (KRT18)
    Alternative Name
    Cytokeratin 18 (KRT18 Antibody Abstract)
    Synonyms
    CK18, K18, Krt1-18, CYK18, DreK18, cb83, dapk1, sb:cb83, wu:fa13f02, wu:fb36b04, krt18, MGC64569, MGC75922, KRT18, keratin 18, keratin 18, type I L homeolog, keratin 18, type I, keratin, type I cytoskeletal 18, K18, simple type I keratin, Keratin, type I cytoskeletal 18, Krt18, KRT18, krt18, krt18.L, LOC700569, LOC100136778, k1c18, LOC100008885
    Background
    Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.Cytokeratin 18 belongs to type I family (acidic cytokeratins).
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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