KRT18 antibody (Keratin 18)

Details for Product anti-KRT18 Antibody No. ABIN94279
Antigen
Reactivity
Mammalian
831
215
213
111
80
58
57
47
43
32
30
28
28
28
22
14
11
9
6
3
2
2
2
1
1
Host
Mouse
546
315
14
7
4
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This KRT18 antibody is un-conjugated
55
43
11
11
11
11
11
11
10
8
8
8
8
8
8
8
8
8
8
8
8
8
3
3
3
3
3
2
2
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
558
360
349
330
244
195
130
86
75
70
40
31
30
18
14
11
2
1
Options
Immunogen Cytoskeleton preparation of epidermal carcinoma cell line A431.
Clone C-04
Isotype IgG1
Specificity The antibody C-04 reacts with Cytokeratin 18 (45 kDa), a member of intermediate filaments subfamily represented in epithelial tissues.
Cross-Reactivity (Details) Mammalian
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name Cytokeratin 18 (KRT18 Antibody Abstract)
Background Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.Cytokeratins 18 belongs to type I family (acidic cytokeratins).
Pathways Apoptosis, Caspase Cascade in Apoptosis
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Image no. 1 for anti-Keratin 18 (KRT18) antibody (ABIN94279) Immunohistochemistry of paraffin-embedded sections (kidney) Immunohistochemistry stai...
Image no. 2 for anti-Keratin 18 (KRT18) antibody (ABIN94279) Immunohistochemistry of paraffin-embedded sections (kidney) Immunohistochemistry stai...
Image no. 3 for anti-Keratin 18 (KRT18) antibody (ABIN94279) Intracellular Flow Cytometry analysis Intracellular flow cytometry analysis of cytoke...
Product cited in: Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: "A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology." in: The Journal of pathology, Vol. 164, Issue 3, pp. 215-24, 1991 (PubMed).

Vojt?sek, Stasková, Nenutil, Lauerová, Kovarík, Rejthar, Bártková, Bártek: "Monoclonal antibodies recognizing different epitopes of cytokeratin No.18." in: Folia biologica, Vol. 35, Issue 6, pp. 373-82, 1990 (PubMed).

Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: "Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread." in: International journal of cancer. Supplement = Journal international du cancer. Supplement, Vol. 3, pp. 50-5, 1989 (PubMed).

Lauerová, Kovarik, Bártek, Rejthar, Vojt?sek: "Novel monoclonal antibodies defining epitope of human cytokeratin 18 molecule." in: Hybridoma, Vol. 7, Issue 5, pp. 495-504, 1989 (PubMed).