Mouse anti-Human IgA Secretory Component Antibody

Catalog No. ABIN94461

Product Details

Target: IgA Secretory Component

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Specificity: The antibody SC-05 reacts with 80 kDa human secretory component glycoprotein (both free and bound in secretory IgA). Recognized glycoprotein is specific membrane marker of glandular carcinomas.

Cross-Reactivity (Details): Human

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Endotoxin Level: Low Endotoxin

Immunogen: Affinity-purified secretory component from human colostrum.

Clone: SC-05

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry (frozen sections): Examples of positive human tissues: secretory mucosa of gastrointestinal and respiratory tract, epithelia of salivary glands, endometrium, endocervix, kidney, prostate, mammary gland. Recommended dilution: 2-8 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

References

Bartek, Bartkova, Taylor-Papadimitriou: "Keratin 19 expression in the adult and developing human mammary gland." in: The Histochemical journal, Vol. 22, Issue 10, pp. 537-44, (1991) (PubMed).

Kvale, Bartek, Sollid, Brandtzaeg: "Rapid selection of cultured cells with increased expression of a membrane marker (secretory component)." in: International journal of cancer. Journal international du cancer, Vol. 42, Issue 4, pp. 638-41, (1988) (PubMed).

Target Details

Target: IgA Secretory Component

Background: Immunoglobulin A SC