Dynamitin antibody (Middle Region)
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- Target See all Dynamitin (DCTN2) Antibodies
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
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Binding Specificity
- AA 191-219, Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Dynamitin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human Dynactin subunit 2 (Center).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of Human Dynactin subunit 2. Genename: DCTN2
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DCTN2 Primary Antibody
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anti-Dynactin 2 (p50) (DCTN2) (AA 1-401) antibody
DCTN2 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 302-401) antibodyDCTN2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 2G7 unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 50-320) antibodyDCTN2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 1-252) antibodyDCTN2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (C-Term) antibodyDCTN2 Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 192-219) antibodyDCTN2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB19599 unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 1-401) antibodyDCTN2 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (C-Term) antibodyDCTN2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (C-Term) antibodyDCTN2 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (N-Term) antibodyDCTN2 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Chicken, Guinea Pig, Xenopus laevis, Zebrafish (Danio rerio), Bat, Hamster WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- Alternative Name
- Dynactin Subunit 2 (DCTN2 Products)
- Background
- This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.Synonyms: 50 kDa dynein-associated polypeptide, DCTN2, DCTN50, Dynactin 2, Dynactin complex 50 kDa subunit, RBP50, p50 dynamitin
- Molecular Weight
- 44231 Da
- Gene ID
- 10540
- NCBI Accession
- NP_006391
- Pathways
- M Phase, Ribonucleoprotein Complex Subunit Organization
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