FGD6 antibody (C-Term)

Catalog No. ABIN952305

Product Details anti-FGD6 Antibody

Target: FGD6 (FYVE, RhoGEF and PH Domain Containing 6 (FGD6))

Binding Specificity: AA 1331-1359, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to FGD6.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 1331-1359 amino acids from the C-terminal region of human FGD6

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FGD6

Target: FGD6 (FYVE, RhoGEF and PH Domain Containing 6 (FGD6))

Alternative Name: FGD6 (FGD6 Products)

Background: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.Synonyms: FYVE, KIAA1362, RhoGEF and PH domain-containing protein 6, ZFYVE24, Zinc finger FYVE domain-containing protein 24

Molecular Weight: 160816 Da

Gene ID: 55785

NCBI Accession: NP_060821