FUT8 antibody (Middle Region)

Catalog No. ABIN952402

Product Details anti-FUT8 Antibody

Target: FUT8 (Fucosyltransferase 8 (Alpha (1,6) Fucosyltransferase) (FUT8))

Binding Specificity: AA 336-364, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Fucosyltransferase 8 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 336-364 amino acids from the Central region of Human Fucosyltransferase 8 Genename: FUT8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FUT8

Target: FUT8 (Fucosyltransferase 8 (Alpha (1,6) Fucosyltransferase) (FUT8))

Alternative Name: Fucosyltransferase 8 (FUT8 Products)

Background: This enzyme belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternatively spliced variants encoding different isoforms have been identified.Synonyms: 6)-fucosyltransferase, 6-fucosyltransferase, Alpha-(1, FUT8, GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1, GDP-fucose-glycoprotein fucosyltransferase, Glycoprotein 6-alpha-L-fucosyltransferase, alpha1-6FucT

Molecular Weight: 66516 Da

Gene ID: 2530

NCBI Accession: NP_835368