KCNH4 antibody (N-Term)

Catalog No. ABIN953002

This Rabbit Polyclonal antibody specifically detects KCNH4 in WB, FACS and EIA. It exhibits reactivity toward Human.

Quick Overview for KCNH4 antibody (N-Term) (ABIN953002)

Target: KCNH4 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 4 (KCNH4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNH4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-KCNH4 Antibody

Binding Specificity: AA 70-100, N-Term

Specificity: This antibody recognizes Human KCNH4 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 70-100 amino acids from the N-terminal region of human KCNH4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KCNH4

Target: KCNH4 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 4 (KCNH4))

Alternative Name: KCNH4

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system.Synonyms: BEC2, Brain-specific eag-like channel 2, ELK channel 1, ELK1, Ether-a-go-go-like potassium channel 1, KCNH4, Potassium voltage-gated channel subfamily H member 4, Voltage-gated potassium channel subunit Kv12.3

Molecular Weight: 111693 Da

Gene ID: 23415

NCBI Accession: NP_036417