MMAA antibody (Methylmalonic Aciduria (Cobalamin Deficiency) Type A) (AA 63-92)

Catalog No. ABIN953465

Product Details anti-MMAA Antibody

Target:

MMAA

Binding Specificity: AA 63-92, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAA antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Specificity: This antibody recognizes Human and Mouse MMAA (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 63~92 amino acids from the N-terminal region of human MMAA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MMAA

Target:

MMAA

Alternative Name: MMAA (MMAA Antibody Abstract)

Synonyms: 2810018E08Rik, AI840684, cblA, methylmalonic aciduria (cobalamin deficiency) type A, methylmalonic aciduria (cobalamin deficiency) cblA type, Mmaa, MMAA

Background: The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl-CoA mutase. Defects in this gene are a cause of methylmalonic aciduria.Synonyms: MGC120010, MGC120011, MGC120012, Methylmalonic aciduria type A, Methylmalonic aciduria type A protein, mitochondrial

Molecular Weight: 46538 Da

Gene ID: 166785

NCBI Accession: NP_758454

Pathways: Monocarboxylic Acid Catabolic Process