NUDT2 antibody (Middle Region)

Catalog No. ABIN953782

Product Details anti-NUDT2 Antibody

Target: NUDT2 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 2 (NUDT2))

Binding Specificity: AA 61-90, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUDT2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes NUDT2 / APAH1.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region between 61-90aa) of human NUDT2 /APAH1.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Target Details for NUDT2

Target: NUDT2 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 2 (NUDT2))

Alternative Name: NUDT2 / APAH1 (NUDT2 Products)

Background: The NUDT2 gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.Synonyms: 5'''-P1 P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Bis(5'-nucleosyl)-tetraphosphatase, Diadenosine 5', Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2

Gene ID: 318

NCBI Accession: NP_001152