PTPN20 antibody (Middle Region)

Catalog No. ABIN954374

Product Details anti-PTPN20 Antibody

Target: PTPN20 (PTPN20B) (Protein Tyrosine Phosphatase, Non-Receptor Type 20B (PTPN20B))

Binding Specificity: AA 185-215, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN20 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody recognizes PTPN20.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 185-215aa) of human PTPN20A.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PTPN20

Target: PTPN20 (PTPN20B) (Protein Tyrosine Phosphatase, Non-Receptor Type 20B (PTPN20B))

Alternative Name: PTPN20 (PTPN20B Products)

Synonyms: bA42B19.1 antibody, typ antibody, Ptpn20 antibody, protein tyrosine phosphatase, non-receptor type 20 antibody, PTPN20 antibody, Ptpn20 antibody

Background: The product of the PTPN20A (and PTPN20B) gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: PTPN20A, PTPN20B, RP11-142I17.1, Tyrosine-protein phosphatase non-receptor type 20

Gene ID: 26095

NCBI Accession: NP_001035816