SCARA5 antibody (C-Term)

Catalog No. ABIN954679

Product Details anti-SCARA5 Antibody

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Binding Specificity: AA 392-421, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCARA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes SCARA5 (C-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 392-421 amino acids from the C-terminal region of Human SCAR5 (NP_776194.2) Genename: SCARA5

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SCARA5

Target: SCARA5 (Scavenger Receptor Class A, Member 5 (SCARA5))

Alternative Name: SCARA5 (SCARA5 Products)

Background: SCARA5 (scavenger receptor class A member 5), also known as Tesr, is a 495 amino acid cell membrane protein. SCARA5 is expressed at high levels in testis, with highest levels specifically found in specific populations of epithelial cells and Sertoli cells. SCARA5 forms a homotrimer single-pass type II membrane complex present on the surface of the plasma membrane. Cells transfected with SCARA5 were able to bind particular gram-positive and gram-negative bacteria, suggesting a possible role for SCARA5 in immunity to infection. It has also been suggested that SCARA5 may be involved in transferrin delivery pathways. Expressed as four isoforms produced by alternative splicing, SCARA5 contains one collagen-like domain and one SRCR domain.Synonyms: Scavenger receptor class A member 5

Gene ID: 286133

NCBI Accession: NP_776194

Pathways: Transition Metal Ion Homeostasis