SEMA3G antibody (Middle Region)

Catalog No. ABIN954720

Product Details anti-SEMA3G Antibody

Target: SEMA3G (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3G (SEMA3G))

Binding Specificity: AA 223-252, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEMA3G antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes SEMA3G (Center).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of Human SEMA3G Genename: SEMA3G

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-SEMA3G antibody (ABIN954720)

Thal, Züchner, Gierer, Schulte, Schöls, Schüle, Synofzik: "Abnormal Paraplegin Expression in Swollen Neurites, τ- and α-Synuclein Pathology in a Case of Hereditary Spastic Paraplegia SPG7 with an Ala510Val Mutation." in: International journal of molecular sciences, Vol. 16, Issue 10, pp. 25050-66, (2016) (PubMed).

Franke, Rickelt, Zimbelmann, Dörflinger, Kuhn, Frey, Heid, Rosin-Arbesfeld et al.: "Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral ..." in: Cell and tissue research, Vol. 359, Issue 3, pp. 779-97, (2015) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Karayan-Tapon, Wager, Guilhot, Levillain, Marquant, Clarhaut, Potiron, Roche: "Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?" in: British journal of cancer, Vol. 99, Issue 7, pp. 1153-60, (2008) (PubMed).

Kigel, Varshavsky, Kessler, Neufeld: "Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells." in: PLoS ONE, Vol. 3, Issue 9, pp. e3287, (2008) (PubMed).

Rikova, Guo, Zeng, Possemato, Yu, Haack, Nardone, Lee, Reeves, Li, Hu, Tan, Stokes, Sullivan, Mitchell, Wetzel, Macneill, Ren, Yuan, Bakalarski, Villen, Kornhauser, Smith, Li, Zhou, Gygi, Gu et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, (2007) (PubMed).

Howell, Shindo, Murray, Gridley, Wilson, Schimenti: "Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations." in: Genetics, Vol. 175, Issue 2, pp. 699-707, (2007) (PubMed).

Fukuda, Mikoshiba: "Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus." in: FEBS letters, Vol. 503, Issue 2-3, pp. 217-8, (2001) (PubMed).

Target Details for SEMA3G

Target: SEMA3G (Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3G (SEMA3G))

Alternative Name: SEMA3G (SEMA3G Products)

Background: SEMA3G has chemorepulsive activities for sympathetic axons. Ligand of NRP2 (By similarity).Synonyms: Semaphorin sem2, Semaphorin-3G

Gene ID: 56920

NCBI Accession: NP_064548