TTC8 antibody (N-Term)

Catalog No. ABIN955378

This Rabbit Polyclonal antibody specifically detects TTC8 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for TTC8 antibody (N-Term) (ABIN955378)

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTC8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TTC8 Antibody

Binding Specificity: AA 17-46, N-Term

Specificity: This antibody detects TTC8 / BBS8 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human TTC8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TTC8

Target: TTC8 (Tetratricopeptide Repeat Domain 8 (TTC8))

Alternative Name: TTC8 / BBS8

Background: This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.Synonyms: Bardet-Biedl syndrome 8 protein, TPR repeat protein 8, Tetratricopeptide repeat protein 8

Gene ID: 123016

NCBI Accession: NP_653197

Pathways: Hedgehog Signaling