SLC25A11 antibody (C-Term)

Catalog No. ABIN966712

Product Details anti-SLC25A11 Antibody

Target: SLC25A11 (Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A11 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human OGCP(Mitochondrial 2-oxoglutarate/malate carrier protein)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-SLC25A11 antibody (ABIN966712)

Kabe, Ohmori, Shinouchi, Tsuboi, Hirao, Azuma, Watanabe, Okura, Handa: "Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier." in: The Journal of biological chemistry, Vol. 281, Issue 42, pp. 31729-35, (2006) (PubMed).

Steiner, Schuff-Werner: "Balancing analytical performance and medical reasoning: is carryover a critical issue in estimating low white blood cell numbers in bone marrow/stem cell transplant recipients?" in: Annals of hematology, Vol. 83, Issue 4, pp. 256-7, (2004) (PubMed).

Piccininni, Iacobazzi, Lauria, Rocchi, Palmieri: "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3." in: Cytogenetics and cell genetics, Vol. 83, Issue 3-4, pp. 256-7, (1999) (PubMed).

Bisaccia, Capobianco, Mazzeo, Palmieri: "The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224." in: FEBS letters, Vol. 392, Issue 1, pp. 54-8, (1996) (PubMed).

Bisaccia, Zara, Capobianco, Iacobazzi, Mazzeo, Palmieri: "The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier." in: Biochimica et biophysica acta, Vol. 1292, Issue 2, pp. 281-88, (1996) (PubMed).

Target Details for SLC25A11

Target: SLC25A11 (Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11))

Alternative Name: OGCP (SLC25A11 Products)

Background: OGCP(Mitochondrial 2-oxoglutarate/malate carrier protein) catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. OGCP is located in mitochondrion inner membrane and is a multi-pass membrane protein. OGCP belongs to the mitochondrial carrier family and contains 3 Solcar repeats.
Synonyms: SLC25A11 (Solute carrier family 25 member 11), SLC20A4,

Pathways: Dicarboxylic Acid Transport