SRC antibody (V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian))

Details for Product anti-SRC Antibody No. ABIN967082
Target
Reactivity
Human, Mouse, Rat
343
196
166
34
32
19
13
12
12
9
9
5
5
5
4
3
3
1
1
1
1
Host
Rabbit
323
39
1
Clonality
Polyclonal
Conjugate
This SRC antibody is un-conjugated
25
19
18
12
12
11
11
8
8
8
8
8
5
5
5
5
5
1
1
Application
Immunohistochemistry (IHC)
256
159
120
66
54
30
25
21
11
8
7
6
4
3
1
Options
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human Src around the phosphorylation site of tyrosine 529 (P-Q-YP-Q-P).
Specificity Src (Ab-529) antibody detects endogenous levels of total Src protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Target
Alternative Name Src (SRC Antibody Abstract)
Pathways JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Benes, Wu, Elia, Dharia, Cantley, Soltoff: "The C2 domain of PKCdelta is a phosphotyrosine binding domain." in: Cell, Vol. 121, Issue 2, pp. 271-80, 2005 (PubMed).

Xu, Harrison, Eck: "Three-dimensional structure of the tyrosine kinase c-Src." in: Nature, Vol. 385, Issue 6617, pp. 595-602, 1997 (PubMed).

Pyper, Bolen: "Identification of a novel neuronal C-SRC exon expressed in human brain." in: Molecular and cellular biology, Vol. 10, Issue 5, pp. 2035-40, 1990 (PubMed).

Parker, Mardon, Lebo, Varmus, Bishop: "Isolation of duplicated human c-src genes located on chromosomes 1 and 20." in: Molecular and cellular biology, Vol. 5, Issue 4, pp. 831-8, 1985 (PubMed).