ZBTB16 antibody (Zinc Finger and BTB Domain Containing 16) Primary Antibody
ZBTB16
Reactivity: Human
ICC, ELISA, WB
Host: Mouse
Monoclonal
5B3
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(1)
Catalog No. ABIN969465
$410.30
Plus shipping costs $45.00
100 μL
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United States
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- Target
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Conjugate
- This ZBTB16 antibody is un-conjugated
- Application
- Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
- Purification
- Ascites
- Immunogen
- Purified recombinant fragment of human ZBTB16 expressed in E. Coli.
- Clone
- 5B3
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Felicetti, Errico, Bottero, Segnalini, Stoppacciaro, Biffoni, Felli, Mattia, Petrini, Colombo, Peschle, Carè: "The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms." in: Cancer research, Vol. 68, Issue 8, pp. 2745-54, 2008 (PubMed).
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Felicetti, Errico, Bottero, Segnalini, Stoppacciaro, Biffoni, Felli, Mattia, Petrini, Colombo, Peschle, Carè: "The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms." in: Cancer research, Vol. 68, Issue 8, pp. 2745-54, 2008 (PubMed).
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- Target
- Alternative Name
- ZBTB16 (ZBTB16 Antibody Abstract)
- Background
- This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
- Molecular Weight
- 74 kDa
- Gene ID
- 7704
- HGNC
- 7704
- Pathways
- Positive Regulation of fat Cell Differentiation
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