Caspase 12 Proteins

4 Caspase 12 (Gene/pseudogene) (CASP12) Proteins from 3 manufacturers are available on www.antibodies-online.com.

Data Quality
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Type
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    Protein
Antigen
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Reactivity
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Application
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Host
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Binding Specificity
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Conjugate
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Protein Type
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Format
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4 Products
Recombinant Protein, Insect Cells (Source), Purity >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ReactivityHuman
Application Crys, ELISA, SDS, WB
Order details Cat. No. ABIN3090819
$6,570.39
Plus shipping costs $45.00 and $22.00 dry ice
Will be delivered in 50 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityMouse (Murine)
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN2122559
$656.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityRat (Rattus)
Application ELISA, IP, SDS, WB
Order details Cat. No. ABIN3008655
$703.49
Plus shipping costs $45.00
Delivery in 11 to 18 Business Days
Recombinant Protein, Escherichia coli (E. coli) (Source), Purity > 95 %
ReactivityRat (Rattus)
Application IP, SDS, ELISA, WB
Order details Cat. No. ABIN2124246
$704.00
Plus shipping costs $45.00
Delivery in 15 to 18 Business Days
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Caspase 12 (CASP12) Protein Profile

Protein Summary

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with Caspase 12 (CASP12)

  • caspase 12 (Casp12) antibody
  • caspase 12 (gene/pseudogene) (CASP12) antibody
  • CASP-12 antibody
  • CASP12P1 antibody

Protein level used designations for CASP12

CASP-12 , caspase-12 , caspase 12 pseudogene 1 , inactive caspase-12

GENE ID SPECIES
12364 Mus musculus
156117 Rattus norvegicus
100506742 Homo sapiens
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