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Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
, Granzyme A
, BLT esterase
, H factor
, Hanukah factor
, autocrine thymic lymphoma granzyme-like serine protease
, serine esterase 1
, t cell-specific serine protease 1
, CTL tryptase
, Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease)
, cytotoxic T-lymphocyte proteinase 1
, h factor